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[Analysis Case] Surface Imaging of Soft Contact Lenses in Liquid AFM

Quantitative evaluation of surface properties can be performed using AFM analysis in an aqueous solution.

There are materials in polymers that change shape depending on the environment. To observe the original shape of the sample, measurements in real environmental conditions are necessary. This document presents a case study that visualizes the surface shape of soft contact lenses in saline solution. By measuring under conditions close to the actual environment, it is possible to evaluate while maintaining the original shape of the sample.

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Tohoku Univ. Technology : Electrically moisturized contact lenses : T18-478

Equipped with bio-battery, electroosmotic flow provides moisturizing effect

With the spread of contact lenses (CLs), the number of patients suffering from dry eye is increasing. In addition, the spread of smart CLs with biomonitoring, communication and display functions is expected in the future, and effective measures against dry eye are required.  The present inventors have developed a CL-type device capable of preventing dry eye based on their long accumulated "hydrogel synthesis and molding technology" and "biocompatible battery power generation technology". Specifically, they developed a hydrogel material with high electroosmotic flow generation efficiency and excellent moldability. They found that when applied to CLs, water flow is generated in the lens by energization, which can maintain the wet state of the CL and stabilize the tear film on the cornea. Furthermore, they have succeeded in mounting a bio-battery on a contact lens to drive it as a self-standing device that does not require external power supply (right figure).  The present invention is important not only for the prevention of dry eye, but also for the controlled release of eyedrops and the control of intraocular pressure by inducing aqueous humor drainage. It is expected to develop as a method for injecting and injecting eyedrops into and out of eye holes, which is similar to eye drops and syringes.

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